Project 3606: M. R. Whitney, L. Mose, C. A. Sidor. 2017. Odontoma in a 255-Million-Year-Old Mammalian Forebearer. JAMA Oncology. 3 (7):998-1000.
Specimen: † Gorgonopsia (NMT RB382)
View: apical root

Abstract

Distinctive mammalian traits, such as endothermy (warm- bloodedness), a muscular diaphragm, large brain size, fur, and a highly specialized dentition, including diphyodonty, prismatic enamel, and a functionally regionalized tooth row (heterodonty), are the product of more than 300 million years of evolutionary divergence from reptiles and other tetrapods. The sequence and timing of these adaptations are captured in the fossil record of premammalian synapsids, but an understanding of the evolutionary context of mammalian disease, including cancer, remains elusive. We report the first instance, to our knowledge, of a tumor in a 255-million-year- old mammalian forebear and comment on the implications for establishing the phylogenetic and physiological conditions under which such pathologic features first arose.


Read the article »

Article DOI: 10.1001/jamaoncol.2016.5417

Project DOI: 10.7934/P3606, http://dx.doi.org/10.7934/P3606
This project contains
  • 2 Media
  • 1 Taxon
  • 1 Specimen
Total size of project's media files: 78 MB

Download Project SDD File
Currently Viewing:
MorphoBank Project 3606
  • Creation Date:
    06 January 2020
  • Publication Date:
    06 January 2020
  • Project views: 161

    This research
    supported by

    Authors' Institutions

    • University of Washington



    Members

    member name taxa specimens media
    Megan Whitney
    Project Administrator
    Last logged in 01/06/20
    112


    Project has no matrices defined.



    Project views

    type number of views Individual items viewed (where applicable)
    Total project views161
    Project overview35
    Media views62Media search (48 views); M683219 (7 views); M683220 (7 views);
    Views for media list21
    Taxon list14
    Specimen list21
    Bibliography8




    Project downloads

    type number of downloads Individual items downloaded (where applicable)
    Total downloads from project4
    Project downloads4